New Triple Quadrupole GC/MS Offers Greater Precision, Selectivity and Sensitivity

Agilent Technologies, Inc introduced the 7000B Triple Quadrupole Gas Chromatograph/Mass Spectrometer (GC/MS/MS), delivering high confidence in ultra-trace level results, while shortening analysis times for target compounds in complex samples. The Agilent 7000B provides femtogram-level sensitivity for analyses such as pesticides, PAHs, PCBs, pyrethroids, THC, and steroids in food, environmental, pharmaceutical, and forensic matrices. The 7000B extends the performance and capabilities of the 7000 Series launched in June 2008 with the introduction of more sensitive electron ionisation (EI) source and a new chemical ionisation (CI) source. All of these improvements are reverse compatible to the 7000A. The new highsensitivity EI source sends more precursor ions to the mass analyser, increasing sensitivity and precision. Source temperature is programmable up to 350oC to accommodate complex matrices. High temperature also means less cleaning, reducing labour requirements and increasing uptime. The source is fabricated of solid inert materials, rather than coated, for durability and stable performance.

The new positive and negative CI source generates ideal precursor ions for MS/MS. Based on the proven CI source of the single quadrupole Agilent 5975C GC/MSD, this PCI/NCI source is built to deliver high sensitivity and trouble-free CI operation. The 7000B MS/MS achieves ultra-fast multiple reaction monitoring (MRM) speed of 500 per second without any ‘cross talk’ between consecutive transitions. High-speed MRM enables users to determine more compounds per ion group than with comparable instruments. Agilent has enhanced the capabilities of the 7890 GC with a new multi-mode inlet and new high-efficiency backflush tools. As compared to traditional column bakeout, backflushing high-boiling matrix extends column life, shortens analysis time, and reduces source maintenance. For high-throughput analyses, the Agilent 7000B can be ordered with the Agilent 7693A Automatic Liquid Sampler (ALS) that automates many bench tasks. The Agilent 7000B GC/MS/MS runs on MassHunter Workstation software, the powerful, intuitive system for instrument control, data acquisition, qualitative and quantitative data analysis, and reporting.