Aminoglycoside and Macrolide Antibiotics Analyser

Antec Leyden has developed integrated system solutions for the analysis of the aminoglycoside and macrolide antibiotics. The system is
dedicated to the analysis of pharmaceutical formulations and bulk products. Aminoglycosides are manufactured by a fermentation process
and the main constituents, including impurities and by-products can be identified and quantified. Samples from different sources can be
analysed as well, for example a veterinary cocktail of Spectinomycin and Lincomycin has been analysed using a step gradient.
For the analysis of Azithromycin a method has been developed that allows analysis of several other macrolides as well.
For pulsed amperometric detection of aminoglycosides Antec Leyden selected the Flexcell electrochemical cell. This cell has an exchangeable working electrode which is particularly useful as electrode consumption occurs in the process. Exchanging for a new electrode disc only takes a few minutes. The HyREF is completely maintenance free even at pH 13 which is required for pulsed amperometric detection. Several application notes are available on their website.