Nanoscale degasser and micro flowmeter

Biotech Fluidics reports how its ultra-low volume degassers and non-invasive micro flowmeter are vital lab tools for nanoscale applications including chromatographic separations, dispensing, diagnostics, drug screening, nucleic acid sequencing and tissue culture.

Studying liquid phenomena at a nanoscale level can be very demanding and requires a device designed to continuously monitor ultra-low fluidic flows in real-time. The Biotech Micro Flow Meter is a high-resolution thermal flow sensor that is extremely accurate and sensitive. This reliable flow sensor is compatible with almost any solvent and being non-invasive guarantees the unperturbed operation of your whole nanofluidic system.

Optimised to operate over the 10nl to 80 µL/minute flow range, with an unmatched high resolution of 1nl / minute, the Biotech Micro Flow Meter is the perfect tool for continuously monitoring the consistency of nanoscale dispensing systems as well as uHPLC and LC/MS solvent / reagent delivery systems. Compact in size, the Micro Flow Meter comes with easy-to-use software app enabling continuous recording, monitoring, and storage of measured flow rate data.

A single gas microbubble in a nanoscale liquid dispenser or pumping system can ruin your operational precision and accuracy. Removing dissolved gases from liquids prior to operation is therefore vital to eliminating the risk of having microbubbles in the fluidic channels.

Biotech Fluidics DEGASi® PLUS Nano and DEGASi® PLUS ultraNano inline degassers are designed to address the challenge of nanofluidic systems by minimising the hold-up volume and offering wide chemical compatibility.

Both the Nano and Nano-Ultra degassers are based on Systec AF membrane making them suitable for water-based media and most organic liquids. The liquid flow path is metal free making these degassers also fully biocompatible.

With an internal volume of only 25µl, the DEGASi® PLUS Nano is designed for degassing fluid flows up to 100 µl /minute. With a hold-up volume of just 6uL the DEGASi® PLUS ultraNano is optimised for extremely low flow applications up to 25 µl /minute. Both degassers are available with up to 6-channels of operation and are available as standalone or integrated devices.

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