ESA Biosciences has developed the first stable, sensitive, and robust analytical system that enables routine measurement of thiols, thioethers, disulfides and other sulphur-containing compounds. Life-science researchers believe that sulphur-containing compounds are critical to a variety of biologically and clinically important processes from oxidative metabolism, to cardiovascular and neurodegenerative-disease mechanisms, to signal transduction. But measuring sulphur-containing compounds has been extraordinarily difficult, until now.
The new ESA system incorporates a specially developed electrochemical cell with a unique Boron Doped Diamond (BDD) working electrode that provides excellent sensitivity and durability, while eliminating the problems (fouling, high background, mobile phase oxidation) associated with earlier ECD systems.