HPLC
Optimising Pump Performance with Early Gas Bubble Detection
Oct 05 2023
Testa Analytical has released a study showcasing the effectiveness of their Solvent Line Monitor in preventing issues caused by undissolved gas bubbles in HPLC, flow chemistry, or liquid dosing systems.
Undissolved gas bubbles can significantly impact the performance of peristaltic pumps, particularly in HPLC systems. While vacuum degassers are commonly used to remove dissolved gas, they are ineffective when it comes to undissolved gas bubbles. These bubbles can bypass the degassing device, reach the peristaltic pump, and cause operational problems and errors in analytical results.
The study provides data demonstrating the influence of dissolved gas on peristaltic pump performance and highlights the adverse effects of undissolved gas bubbles. Testa Analytical's Solvent Line Monitor offers a practical solution to address this issue.
This innovative device features optical and acoustic alarms, along with a digital output that can halt a chromatography or flow chemistry pump before an undissolved gas bubble disrupts its operation. The Solvent Line Monitor is user-friendly and programmable, allowing adjustments in sensitivity, operating mode, and bubble detection alarms. The setup process is straightforward, facilitated by an intuitive PC-based application included with each Solvent Line Monitor. Users can configure parameters such as minimum bubble size, frequency, and the number of bubbles, and specify actions to take upon detecting an alarm, whether it's a simple beep or a complete pump stop.
Read the in-depth study in full.
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