• Rapidly Standardise and Scale Your ChIP Workflows  

Laboratory Products

Rapidly Standardise and Scale Your ChIP Workflows  

Jan 31 2019

Chromatrap® has entered into a partnership with Covaris to offer a highly scalable and simple ChIP workflow enabling researchers to easily isolate protein-DNA complexes for downstream applications, such as ChIP-Seq, ChIP-qPCR, Next-generation sequencing (NGS), and Mass Spectrometry (MS).

Preparing samples for Chromatin Immunoprecipitation (ChIP) has traditionally been a multi-step, time-consuming, and error-prone workflow. Pairing the bead-free Chromatrap immunoprecipitation system with the Covaris truChIP® and AFA® sample preparation technologies enables investigators to rapidly profile protein-DNA interactions of interest. By combining the two technologies, researchers now have access to a compatible and optimised workflow that increases productivity and allows the user to gain better results with higher quality samples.

Chromatrap, the revolutionary automation-compatible spin column-based approach eliminates many of the challenges encountered when working with magnetic beads. This rapid centrifugation-based protocol requires only 3 simple washes using individual spin columns or 96-well plates and can be completed in a single day. In contrast, typical bead-based workflows take around 10 hours with over 10 wash steps and incubations.

Using the Covaris Adaptive Focused Acoustics® (AFA®) technology, researchers can easily isolate and reproducibly shear soluble chromatin without disrupting the protein-DNA interactions for immunoprecipitation with bead-free Chromatrap Protein A and G ChIP kits.


Digital Edition

International Labmate 49.6 - Sept 2024

September 2024

Chromatography Articles - HPLC gradient validation using non-invasive flowmeters Mass Spectrometry & Spectroscopy Articles - From R&D to QC, making NMR accessible for everyone: Putting NMR...

View all digital editions

Events

ISSS 2024

Sep 22 2024 Messina, Italy

19th Confocal Raman Imaging Symposium

Sep 23 2024 Ulm, Germany

Control-Tech

Sep 24 2024 Kielce, Poland

WoTS - World of Technology and Science

Sep 24 2024 Utrecht, Holland

Cleanzone 2024

Sep 25 2024 Frankfurt am Main, Germany

View all events