Automated sample prep enhances LC/GC cannabis analysis

Tecan introduces the Resolvex Prep, an ideal solution for automating cannabis analysis workflows while using the same labware as manual processes. This platform offers automated syringe change, a wash station, and the ability to pipette into/out of septa-sealed vials, all while precisely handling solvents used in LC/LCMS and GC/GCMS analysis.

Starting with weighed cannabis flowers, the Resolvex Prep automates the entire sample preparation process of extraction, filtration, and final solution preparation, directly into 2 mL autosampler vials, for subsequent chromatographic analysis. 

Recent demonstrations have shown excellent performance compared to the previous GMP-validated manual protocol, achieving THCA concentrations of approximately 25.4% and a recovery rate of 99.1% along with a 97.5% recovery rate for terpenoids, confirming the method’s reliability and efficiency. 

The Resolvex Prep is capable of handling a wide range of sample matrices including plants, water and soil. It supports various extraction methods, such as SPE and LLE, enhancing its adaptability for diverse applications.

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