Paracetamol in Tablets: Fully Automated Sample Preparation and Analysis by Liquid Chromatography

Paracetamol is a very effective analgesic and antipyretic drug. The present application describes its determination in tablets by reversed-phase chromatography and UV detection. Fully automated sample preparation is included and provided by an 815 Robotic Soliprep for liquid chromatography. 

The 815 Robotic Soliprep LC is a robust autosampler providing everything, starting from tablet dissolution to homogenisation and filtration to the injection with a 250 nL internal loop on the chromatography system.

Integrated sample preparation and analysis as enabled by the system described increases sample throughput while improving reproducibility and reliability of results.

For more information on this press release please contact the Marketing Department at Metrohm UK Ltd.