Mass Spectrometry & Spectroscopy

  • Innovative Cell Counter and Spectrometer in One Device

Innovative Cell Counter and Spectrometer in One Device

Jan 14 2021 Read 3190 Times

Anvajo is an innovative technology company that develops and produces point-of-care solutions for the analysis of a wide range of liquids at its site in Dresden. Anvajo have teamed up with Scientific Laboratory Supplies (SLS), the UKs largest independent supplier of scientific products to make their revolutionary device available to laboratories across the United Kingdom and Ireland.  

The fluidlab R-300 is a portable device that combines the two central laboratory technologies of spectrometry and automated cell counting. It combines the world's smallest available spectrometer with an AI-based automated cell counter based on a new holographic microscopy technique. The Anvajo technology enables the user to quantify a wide variety of cell types in suspension and to perform spectrometric analyses. The fluidlab R-300 can be used in biotechnological, biochemical, and microbiological laboratories as well as in all areas where research is carried out with cell cultures or where liquids are chemically analysed on the basis of absorption or scattered light measurement.

Intuitive operation and precise results make the fluidlab R-300 the laboratory instrument of the future, replacing large and expensive stand-alone instruments. With the help of a simple adapter system, both standard cuvettes and glass sample carriers can be used for a variety of analyses such as absorbance, automatic cell counting and label-free viability measurements.

Using a pipette, the cell suspension or the liquid is analysed by simply placing on a sample carrier to be analysed with the instrument. A separate computer or other devices are no longer necessary. The glass sample carrier from Anvajo can also be used under a normal microscope, if desired.

Due to an innovative holographic microscopy approach, Anvajo's cell counter has a much larger ‘field of view’ compared to other cell counters. This means that significantly more cells are counted, which in turn ensures increased statistical certainty.

In addition to pure cell counting, the viability of the cells (differentiation between living and dead cells) can be measured with the R-300 without staining. Staining with e.g. trypan blue is not required. Cytotoxic effects and measurement errors are eliminated by the label-free determination.

Cell counts are performed accurately and automatically within 40 seconds. The error-prone, time-consuming counting of cell cultures in a haemocytometer can thus be dispensed with. Only the smallest sample volumes of 4 μl to 20 μl are required for analysis with the fluidlab R-300.

In addition to the holographic microscope, the fluidlab contains the world's smallest spectrometer in the wavelength range from 375 to 700 nm with a spectral resolution of less than 2 nm. In the value range of 0 - 2.5 absorbance units, the fluildab R-300 is linear with a photometric accuracy of 0.01. This allows the user to read out a variety of colorimetric and turbidimetric assays or to perform classical optical density measurements (e.g. OD 600).

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