SepSolve Analytical – Smart Subtract

Best separation
science innovation

Smart Subtract deserves to win a Labmate Award for Best Separation Science Innovation because it revolutionises the process of chromatographic comparison for GC–MS and GC×GC–MS data. 

Traditional methods of comparing chromatograms are often slow and time-consuming, and minor but crucial differences are all too easily missed. mart Subtract addresses these challenges by offering a quick and efficient way to compare two data files and highlight key differences in just minutes.

Smart Subtract uses a probability-based subtraction algorithm to rapidly highlight the key differences between pairs of 1D or 2D GC chromatograms, bringing a new level of efficiency and confidence to comparative workflows. In regular chromatographic subtraction, small relative differences between high-intensity peaks often dominate the subtracted chromatogram. Smart Subtract suppresses these small relative differences, resulting in a cleaner background that makes the significant differences easier to spot.

Additionally, the subtracted chromatograms produced by Smart Subtract can be processed using standard techniques, including automated integration and library searching, to rapidly generate reports on key differences. The software’s straightforward workflow ensures that results can be communicated easily to non-experts or stakeholders, with no need for advanced statistical knowledge.

Smart Subtract is also highly versatile, supporting a broad range of file formats for both 1D and 2D GC–MS data, ensuring seamless integration into existing workflows. Its user-friendly interface means that anyone, regardless of their expertise in statistical methods, can quickly gain valuable insights.

In short, Smart Subtract streamlines the process of chromatographic comparisons, making it faster, simpler, and more effective.