Highly Specific Aptamer Protein Precipitation Kits

Amsbio has announced a new range of Aptamer Protein Precipitation Kits that bind with unmatched high specificity and affinity to target molecules.

The new Amsbio Aptoprecipitation (AP) / Co-aptoprecipitation (Co-AP) Kits are aptamer based protein precipitation kits designed to provide easy, quick and consistent protein precipitation. The new kits offer a range of unique characteristics and provide significant advantages over alternative methods.

Based upon a proprietary oligonucleotide - Aptamer kits will not contribute to protein/peptide background that can interfere with subsequent mass analysis. Supplied as a complete kit in which aptamer is covalently conjugated to magnetic beads, you can perform successful pull down experiments with ease, without the traditional troublesome conjugation step. Unlike antibody based protein precipitation methods - Aptamer is highly specific recognising just the native form of target proteins, not the denatured form. The mild elution conditions used with Aptamer kits enable isolation of intact proteins and protein complexes.

Benefiting from a long shelf life at room temperature, covalent magnetic bead immobilisation and mild elution methodology the Amsbio aptamer (AP) resin can be reused. The prepared aptamer-conjugated magnetic beads can be regenerated and reused several times for AP / Co- AP assays without any significant loss in binding capacity.