Fast, automated plasmid DNA isolation for small-scale research

Thermo Fisher Scientific has introduced the Applied Biosystems™ MagMAX™ Pro HT NoSpin Plasmid MiniPrep Kit to meet the growing need for fast, automated plasmid DNA isolation. Designed for small-scale experiments, the kit enables researchers to quickly and affordably isolate high-quality plasmid DNA, essential for therapeutic research into infectious diseases, cancer, and genetic disorders.

The MagMAX Pro HT NoSpin Kit is among the fastest plasmid purification systems available. Using just 1 millilitre of fresh culture, it allows 96 minipreps to be completed in under 35 minutes - including setup - on a Thermo Scientific™ KingFisher™ instrument. Its automation-ready design supports effortless scaling from benchtop workflows to high-throughput operations.

This kit removes time-consuming manual steps such as cell pelleting and offline lysis, which usually require repetitive centrifugation or filtration, streamlining the purification process and increasing lab efficiency. It uses advanced magnetic bead technology and eco-friendly chemistry to reduce reagent waste and lower operational costs, making plasmid isolation accessible to more laboratories.

“Labs of all sizes need solutions that speed research and eliminate bottlenecks,” said Kevin Lowitz, VP of Sample Preparation at Thermo Fisher Scientific. “By automating plasmid purification and using minimal culture volumes, scientists can run more experiments efficiently, save time and resources, and accelerate their projects.”

For larger volume needs, Thermo Fisher offers the KingFisher™ PlasmidPro Maxi Processor, a fully automated system that processes 150 mL bacterial culture in 75 minutes to yield transfection-grade plasmid DNA with over 80% supercoiled form - without centrifugation or manual steps.

The MagMAX Pro HT NoSpin Kit suits biotech, pharma, CROs, CDMOs, and academic labs requiring high-quality plasmid DNA for early-stage therapeutic and vaccine research. It delivers up to 20 µg of high-copy plasmid DNA per 1 mL culture, compatible with sensitive cell lines and a wide range of downstream applications such as cloning, sequencing, and transfection.

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