Laboratory Products

  • New High-Throughput Recombinant Antibody Production Service Launched

New High-Throughput Recombinant Antibody Production Service Launched

Mar 27 2020 Read 250 Times

Absolute Antibody Ltd has announced the launch of its FleXpress™ high-throughput recombinant antibody production service, which offers customers the flexibility to rapidly express a large number of antibodies at 80 ml scale.
 
The high-throughput recombinant antibody production service is ideal for early-stage pharmaceutical researchers conducting pilot studies on a group of therapeutic antibody candidates, as well as reagent companies with a monoclonal antibody portfolio interested in converting their collection from hybridomas to recombinant production. Recombinant antibodies, long the standard in pharmaceutical development, are becoming increasingly popular for research and diagnostic applications due to their superior batch-to-batch reproducibility, antibody engineering options, and guaranteed long-term supply.
 
The antibody production service utilises Absolute Antibody’s HEXpress™ antibody expression platform, a serum-free, mammalian transient expression system that offers a faster, more affordable alternative to stable CHO cell line generation. The proprietary system produces high-quality recombinant antibodies in any species, isotype or format, including multispecifics and fragments, with high purity and low endotoxin levels.
 
The FleXpress™ production line can recombinantly manufacture hundreds of different antibodies per week at 80 ml scale, allowing Absolute Antibody to quickly respond to customer needs for high-throughput small-to-medium-scale recombinant antibody production. It joins two other production lines at the company’s antibody manufacturing facility, which also offers the option to scale to multi-gram quantities in a matter of weeks.
 
“Absolute Antibody specialises in recombinant antibody technology, and we’ve developed a robust and reliable platform for high-throughput antibody production at relatively small scales,” said Catherine Bladen, PhD, Chief Operations Officer at Absolute Antibody. “Our new production line gives our customers the flexibility to rapidly and cost-effectively test recombinant versions of many different antibodies using our proven recombinant expression technology.”
 
In 2019, Absolute Antibody produced thousands of different recombinant antibodies, making 120 grams of protein in total, for customers across pharmaceuticals, biotechnology, research reagents, diagnostics, and academia. Since its founding in 2012, the company has also used its production platform to build a unique recombinant antibody catalogue consisting of nearly 5,000 antibodies, all benefitting from antibody engineering technology. The FleXpress™ production service enables customers to utilise this same technology for their own recombinant antibody projects.
 

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment




Digital Edition

Labmate UK & Ireland April 2020

April 2020

In This Edition Articles - Export experts talk Corona Virus - Automated cell counting shouldn’t cost the earth Laboratory Products - Spectrophotometer Linearity Validation - Analysi...

View all digital editions

Events

ASMS Conference - ONLINE EVENT

May 31 2020 Houston, TX, USA

PREP 2020 - EVENT CANCELLED

May 31 2020 Baltimore, MD, USA

Laborama 2020 - ONLINE EVENT

Jun 11 2020 Brussels, Belgium

HPLC 2020 - EVENT CANCELLED

Jun 20 2020 San Diego, CA, USA

MedtecLIVE - ONLINE EVENT

Jun 30 2020 Nuremberg, Germany

View all events