Mixer Mill for Biological Applications and Cell Disruption

Mixer mills are widely used for homogenising biological samples such as tissue, liver, muscle, plants, corn or sputum. For cell disruption via bead beating mixer mills are also the perfect solution. 

Retsch’s new Mixer Mill MM 500 vario is a versatile bench-top unit which provides ultimate performance with maximum flexibility for sample homogenisation. It accommodates adapters for different single-use vials of 0.2 ml/1.5 ml/2 ml/5 ml.

Depending on the tube and the type of adapter, 5-10 tubes can be inserted per adapter, resulting in the following maximum vial capacity per batch: 50 x 1.5 or 2 ml (or 60 x 0.2 ml) or 20 x 5 ml.

Typical grinding/homogenising processes of biological materials take less than 2 minutes. Cell disruption with a good reproducibility and efficiency takes 20 sec to 5 min, depending on the cell type. Cryogenic grinding in single-use vials can also be a suitable way to pulverise tough or temperature-sensitive samples in the MM 500 vario.

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