Validated reagent kits for HCP quantification

Gyros Protein Technologies AB, a leader in automated nanolitre-scale immunoassays and advanced peptide synthesis, has announced the release of two new host cell protein (HCP) quantification kits: the Gyrolab® HEK293 HCP Type SN Kit Reagents and Gyrolab HEK293 HCP Type CL Kit Reagents. These kits, developed in collaboration with BioGenes GmbH, are designed to support streamlined and sensitive HCP detection in biotherapeutics derived from HEK293 cell lines.

HCP removal is essential in biologics development to ensure product purity and safety. These impurities can provoke immune responses ranging from mild allergic reactions to severe complications, making their removal a regulatory and clinical priority. The new Gyrolab kits offer a robust solution for detecting HCPs with improved sensitivity and broad antigen coverage.

The kits are fully validated and ready to use on Gyros Protein Technologies’ automated Gyrolab immunoassay platform. By offering pre-optimised, plug-and-play reagent kits, the company enables faster, more reproducible HCP analysis with reduced sample and reagent consumption - improving both throughput and efficiency in analytical workflows

While Gyrolab users have previously been able to use BioGenes’ antibodies with custom methods, the launch of these standardised kits simplifies implementation and enhances performance. The kits benefit from BioGenes’ proprietary 360-HCP antibody development strategy, which uses multiple host species, refined antigen preparation, and optimised purification to ensure exceptional antigen coverage and antibody quality.

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