Chiral and Achiral Separations

Scientists, like good mountaineers, know their destination and what it takes to get there: good support, experience, proper training, a little luck, and the right equipment. As analytical scientists push themselves to reach their next destination, they can count on innovations from Waters. Introducing the ACQUITY UPSFCTM System from Waters. Built on Waters UltraPerformance LC® (UPLC®) platform that revolutionised the industry in 2004, this game-changing UPSFC solution enables scientists to conduct normalphase chromatographic separations using carbon dioxide as the primary mobile phase rather than toxic solvents. Now scientists can minimise harmful waste while gaining superior

separation, resolution, and speed.

The ACQUITY UPSFC System offers the ruggedness and dependability scientists are looking for, with the ease of use they’ve come to expect from liquid chromatography. As an ideal complement to reversed-phase LC this system maximises the benefits of Waters chemistries and informatics to drive a wide range of scientific endeavors - including chiral and achiral applications.

The ACQUITY UPSFC System is a holistically designed system, based on Waters proven ACQUITY UPLC technology. And it opens up entirely new vistas - including different selectivity, improved resolution, and better retention of polar compounds.

The system is fully compatible with Waters industry leading Empower™ and MassLynx™ informatics software, its family of ViridisTM SFC Columns that is specifically designed for this technique, and Waters mass detectors.

For chiral and achiral separations, nothing produces better peak shapes and allows scientists to see and do more than ACQUITY UPSFC. The superior sensitivity and separations capability of ACQUITY UPSFC enables scientists to rapidly confirm the purity of compounds, determine the enantiomeric excess, and increase their range of analytical capability. Compared to normal phase chromatography, UPSFC offers shorter cycle times, faster reequilibration,

and superior resolution. With higher throughput, this means better results and productivity - saving laboratories time and money. The ACQUITY UPSFC System is based on technology that thousands of laboratories are already familiar with and alleviates difficulties related to unforeseen variables that plague normal-phase experiments. With ACQUITY UPSFC, scientists have greater separation power, selectivity, and speed and the ability to get to where they want to go faster and with greater confidence in their results.