• Essential Tools for COVID-19 Omicron Research
    New tools for COVID-19 Omicron variant research from AMSBIO.

Laboratory Products

Essential Tools for COVID-19 Omicron Research

Mar 29 2022

AMSBIO has introduced further essential tools for SARS-CoV-2 researchers to help decipher the COVID-19 B.1.1.529 variant.

New kits expand COVID-19 research portfolio

New to the AMSBIO range are recombinant proteins, easy-to-perform assay kits, Omicron pseudotyped lentiviruses and spike neutralising antibodies for use in functional assays to block SARS-CoV-2 spike protein and ACE2 binding.

The importance of screening for small molecule and antibody inhibitors

Screening for small molecule and antibody inhibitors is an important factor in assisting the discovery of treatments and vaccines for COVID-19 variants. ACE2, Spike, and the 3CL/Main protease are all potential therapeutic targets for the SARS-CoV-2 viral infection triggering this highly infectious disease. AMSBIO has introduced a range of Omicron assay kits for testing interactions with these targets and their respective pathways. Requiring no time-consuming wash steps, these easy-to-perform assay kits come in a variety of read-out detection methods including TR-FRET, fluorogenic, colorimetric, and chemiluminescence. These new kits are ideal for use in validation studies and suitable for rapid high-throughput screening of SARS-CoV-2 inhibitors.

Expressing B1.1.529 S protein, Omicron pseudoviruses from AMSBIO are invaluable tools for measuring inhibitory molecules when used in tandem with ACE2 recombinant cell lines or for measuring the activity neutralising antibodies. AMSBIO’s novel Omicron lentiviruses contain either luciferase or eGFP reporter genes that provide convenient readout of transduction.

Also new to the market are a range of Omicron variant recombinant proteins including Nucleocapsid protein, 3CL Protease and Spike trimer (S1+S2) developed for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

More information online


Digital Edition

International Labmate Buyers Guide 2022

June 2022

In This Edition Evaluation of Recovery of Basic Analytes Using a Mixed-Mode Strong Cation Exchange SPE Microplate by HPLC-MS The Benefits of SEC-MALLS in Biopharmaceutical Applications...

View all digital editions

Events

AACC Annual Meeting & Clinical Lab Expo

Jul 24 2022 Chicago, IL, USA

ICMGP 2022

Jul 24 2022 Virtual event

ACS National Meeting & Expo, Fall 2022

Aug 21 2022 Chicago, IL, USA & Online

ACHEMA 2022 - NEW DATES

Aug 22 2022 Frankfurt, Germany

IMSC 2022

Aug 27 2022 Maastricht, Netherlands

View all events