Miniaturisation of Large-Scale Testing Procedures

As a leading technology partner for the diagnostic and pharmaceutical industry Greiner Bio-One is introducing its new CELLreactor. The innovative 50ml  polypropylene filter top tube enables the miniaturisation of large-scale setups while simultaneously maximising the number of parallel experiments. It can therefore be used as a small bioreactor for the cultivation of cells.

Each CELLreactor cap on the 11.5cm long tube has eight holes and contains a polytetrafluorethylene-coated USP Class VI certified capillary pore membrane. With a pore size of 0.2μm, the membrane not only keeps the contents of the tube completely sterile, but also ensures an excellent gas exchange. Liquids are mixed using stan-dard shakers in order to minimise the formation of foam and any cellular shearing forces during the cultivation process. Due to its conical design, the tube fits into all standard 50ml centrifuge rotors and the cells can be sedimented directly within the tube.

In addition to applications in the field of cell cultures, the CELLreactor is also suitable for the expansion of aerobic bacteria, yeasts and other microorganisms in suspen-sion culture and for storing components and liquids that require gas exchange.