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Liquid chromatography (LC) is a versatile analytical technique used to separate, identify, and quantify components in a liquid mixture. It involves passing a liquid sample through a column packed with a solid stationary phase, where different compounds in the sample interact with the stationary phase to varying degrees, causing them to separate as they move through the column. LC is widely used in pharmaceuticals, environmental testing, and food analysis. Advanced forms like high-performance liquid chromatography (HPLC) offer enhanced resolution and sensitivity for complex mixtures.

ILM 51.5 July 2026

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