Mass Spectrometry & Spectroscopy
Mass Spectrometry Sample Preparation for Nylon 6,6 Analysis
Mar 01 2022
A new technical note from BioChromato compares Evolved Gas Analysis (EGA) and Thermal Desorption (DART) as sample preparation methods for Mass Spectrometry analysis of Nylon 6,6.
Synthesised by polycondensation of hexamethylenediamine and adipic acid, Nylon 6,6 is a polyamide or nylon that is commonly used in the textile and plastic industries. Nylon 6,6 is a polymer of choice when high mechanical strength, rigidity, good stability under heat and/or chemical resistance are required. In the technical note the authors compare ionRocket-DART®-MS to EGA-MS for analysis of Nylon 6,6 samples.
Evolved Gas Analysis has traditionally been used as a mass spectrometry sample preparation technique for polymers, plastics, and fibres. However, analysis by EGA-MS generates fragment ions and requires a database to confirm the identity of the mass fragments.
By comparison, the authors demonstrate how using ionRocket-DART/MS you can observe the parent ion without fragment ions because DART is a soft ionisation technique. Consequently, ionRocket-DART/MS can provide qualitative analysis even if customers cannot find an objective mass fragment within their EGA/MS database.
The ionRocket is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionisation and analysis by mass spectrometry. Using ionRocket a temperature gradient from ambient up to 600ºC can be achieved in just a few minutes. This enables polymers, plastics, and fibres to be pyrolysed and then introduced into the DART®-MS gas stream.
Read this application report in full.
More information online
Digital Edition
International Labmate Buyers Guide 2022
June 2022
In This Edition Evaluation of Recovery of Basic Analytes Using a Mixed-Mode Strong Cation Exchange SPE Microplate by HPLC-MS The Benefits of SEC-MALLS in Biopharmaceutical Applications...
View all digital editions
Events
AACC Annual Meeting & Clinical Lab Expo
Jul 24 2022 Chicago, IL, USA
Jul 24 2022 Virtual event
ACS National Meeting & Expo, Fall 2022
Aug 21 2022 Chicago, IL, USA & Online
Aug 22 2022 Frankfurt, Germany
Aug 27 2022 Maastricht, Netherlands