• Mass Spectrometry Sample Preparation for Nylon 6,6 Analysis
    Close-up of an ionRocket DART-MS system.
  • Structure of Nylon 6,6.

Mass spectrometry & spectroscopy

Mass Spectrometry Sample Preparation for Nylon 6,6 Analysis

A new technical note from BioChromato compares Evolved Gas Analysis (EGA) and Thermal Desorption (DART) as sample preparation methods for Mass Spectrometry analysis of Nylon 6,6.

Synthesised by polycondensation of hexamethylenediamine and adipic acid, Nylon 6,6 is a polyamide or nylon that is commonly used in the textile and plastic industries. Nylon 6,6 is a polymer of choice when high mechanical strength, rigidity, good stability under heat and/or chemical resistance are required. In the technical note the authors compare ionRocket-DART®-MS to EGA-MS for analysis of Nylon 6,6 samples.

Evolved Gas Analysis has traditionally been used as a mass spectrometry sample preparation technique for polymers, plastics, and fibres. However, analysis by EGA-MS generates fragment ions and requires a database to confirm the identity of the mass fragments.

By comparison, the authors demonstrate how using ionRocket-DART/MS you can observe the parent ion without fragment ions because DART is a soft ionisation technique. Consequently, ionRocket-DART/MS can provide qualitative analysis even if customers cannot find an objective mass fragment within their EGA/MS database.

The ionRocket is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionisation and analysis by mass spectrometry. Using ionRocket a temperature gradient from ambient up to 600ºC can be achieved in just a few minutes. This enables polymers, plastics, and fibres to be pyrolysed and then introduced into the DART®-MS gas stream.

Read this application report in full.

More information online


Digital Edition

ILM Guide 2025/26

June 2025

Buyers' Guide Listings- Product Listings by Category- Suppliers Listings (A-Z)Chromatography Articles- Setting the power coefficient and the baseline to linearise the signal of the evaporative ligh...

View all digital editions

Events

AUTOMATICON

Jun 24 2025 Warsaw, Poland

CPhI & P-MEC China 2025

Jun 24 2025 Shanghai, China

Discovery & Development Europe 2025

Jul 01 2025 Basel, Switzerland

MMC 2025

Jul 01 2025 Manchester, UK

analytica Lab Africa

Jul 08 2025 Johannesburg, South Africa

View all events