Microscopy & Microtechniques

  • How to Deter Mosquitoes - With Your Blood

How to Deter Mosquitoes - With Your Blood

Apr 23 2019 Read 1015 Times

Malaria is one of the world's biggest killers, with the mosquito-borne disease claiming more than 400,000 lives in 2017. Now, a study claims that making human blood toxic to mosquitos could stop the spread of malaria and eventually wipe out the disease altogether.

While an increase in global prevention and control strategies has reduced malaria mortality rates by 29% since 2010, almost half of the global population are at risk of contracting the disease. Most cases are reported in Sub-Saharan Africa, though there's an ongoing risk that malaria could spread to other countries.  

Everyday drug proves fatal to malaria-carrying mosquitos

In a breakthrough study, a team of researchers led by Dr Brian D Foy of Colorado State University discovered that malaria-carrying mosquitos immediately die after drinking blood containing traces of ivermectin, a drug used to treat parasite infestations like scabies, river blindness and headlice.

"Ivermectin reduces new cases of malaria by making a person's blood lethal to the mosquitoes who bite them, killing mosquitoes and therefore reducing the likelihood of infection of others,” explains Foy in a statement. “Because ivermectin has a unique mode of action compared to other malaria control insecticides and antimalarial drugs, it could be used alongside drugs that treat malaria to combat residual transmission of the disease."

A breakthrough in the fight against antimalarial drug resistance

The study involved a randomised trial of 2700 people, including 590 children. All participants were given a single dose of ivermectin, with 1,447 individuals administered with additional doses of ivermectin three times a week. The team recorded malaria cases over an 18-week period and found that extra doses of ivermectin translated to a 20% risk reduction of contracting the tropical disease. Furthermore, the number of children who didn't contract malaria at all increased by more than 50% in the group that received extra doses of ivermectin.

Foy stresses that in the wake of antimalarial drug resistance, the need for new disease prevention strategies is imminent. While death rates have been steadily declining for the past decade, he warns that the Plasmodium parasite is beginning to develop resistance to artemisinin, one of the most effective antimalarial drugs.

“Because of mosquitoes' ability to adapt to control tools, new methods of preventing the transmission of malaria are needed, in particular, those that target residual transmission," adds Foy. "Ivermectin is well tolerated and widely used so it could be a useful tool in disease reduction if further trials show similar results."  

Next generation technology plays a key role in supporting laboratory experiments, powering human trials and fast-tracking medical breakthroughs. For a closer look at the latest sophisticated surveying equipment being used to inspect sites prior to system installation, don't miss 'Surveying Sites for Electron Microscopes'.

Reader comments

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.

Post a Comment

Digital Edition

International Labmate July 2019

July 2019

In This Edition Mass Spectrometry & Spectroscopy - 67th ASMS Conference on Mass Spectrometry and Allied Topics - Modular MS Bench System with Integrated Gas Supply for Sciex LC-MS/MS Unveile...

View all digital editions


AACC Annual Meeting & Clinical Lab Expo

Aug 04 2019 Anaheim, CA, USA

M&M 2019

Aug 04 2019 Portland, OR, USA

DXC 2019

Aug 05 2019 Lombard, IL, USA

ACS National Meeting & Expo, Fall 2019

Aug 25 2019 San Diego, CA, USA

Microscopy Conference 2019

Sep 01 2019 Berlin, Germany

View all events