New spinning disk confocal microscopes for live-cell imaging

Two spinning disk confocal microscopes - IXplore IX85 SpinXL and SpinSR - have been introduced by Evident to support advanced live-cell imaging and super-resolution studies. Both systems are built on the IXplore IX85 automated inverted platform and offer improved acquisition speed, resolution, and sample protection.

The SpinXL, based on CrestOptics X-Light technology, delivers a 26.5 mm field number for rapid screening of large areas. Dual-camera support and near-infrared compatibility enable deeper imaging with minimal phototoxicity, making it well-suited for dynamic, high-throughput experiments.

The SpinSR, incorporating Yokogawa CSU-W1 technology and the TruSight SR algorithm, achieves lateral resolution down to 120 nm. It enables detailed time-lapse imaging of subcellular structures, with real-time control and intensity-preserving processing suitable for quantitative workflows. A 3D processing algorithm extends performance into organoid and deep-tissue samples.

Both systems are compatible with the LUPLAPO25XS silicone immersion objective, enabling improved 3D volumetric reconstruction and imaging at depth.

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