NIBRT Installs Fill-finish System to Enhance Training Capability

The National Institute for Bioprocessing Research and Training (NIBRT) is installing an SP Scientific Products’ modular multi-container filling line and isolation system to enhance its training offerings in aseptic biopharmaceutical fill-finish operations at its global centre of excellence in Dublin, Ireland. The SP i-Dositecno robotic filling and stoppering system for pre-sterilised vials, syringes and cartridges in a nested format, as well as a vial capper, is expected to be installed by Spring 2022.

With drugs increasingly aimed at smaller patient groups, such as highly targeted oncology therapeutics, personalised medicines and orphan drugs, the biopharmaceutical industry has seen a growth in demand for efficient, cost-effective technology and robust aseptic manufacturing. Provision of essential training and skills development for operation of these advanced biochemical production systems are delivered by NIBRT through hands-on training in an environment that replicates a modern, working industrial bioprocessing facility.

“We are proud to be recognised and selected by such a respected institute to contribute to the superior training that NIBRT offers in its realistic GMP simulated, operational manufacturing environment,” said Brian Larkin, President & CEO, SP Industries. “Our SP i-Dositecno aseptic filling line reflects the very latest industry standards for automated filling and checking of containers in nested tubs, fulfilling NIBRT’s need to train on the most advanced manufacturing equipment.” 

Including an integrated particle counter for environmental monitoring (EM) and automated container rejection capability, the NIBRT system has an ESCO isolator on the filling unit and an open restricted access barrier system (RABS) for debagging/de-lidding, de-nesting and capping stations, achieving reduction in operating costs in lieu of an isolator, while providing he barrier to the operation and simulate cleanroom conditions as closely as possible.

“We are looking forward to developing a new and optimised fill-finish training curriculum involving our SP i-Dositecno equipment, which will bolster and enhance the training experience we currently offer. Thanks to SP’s technologically advanced filling solution and isolator technology, NIBRT’s training offering will be more reflective of processes used by our valued clients,” said Aoife Barron, Training Team Lead and Fill-Finish SME, NIBRT. “As well as securing the best equipment for aseptic manufacturing, SP’s ability to understand our requirements, provide technical expertise in responding to our inquiries and to rapidly quote, build and install a modular fill-finish solution was also a major factor in our purchasing decision. The system can also be reconfigured easily to grow with our needs and we plan to add the capping station at a later stage.”

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