Microlute® CP: SPE performance you can count on

Sample preparation

Microlute® CP: SPE performance you can count on

23 Jan, 2026

Sample preparation is essential for accurate, robust and reproducible analysis. Solid phase extraction (SPE) offers the cleanest extracts for injection. However, the traditional loose packed form of SPE has inherent issues that can compromise the quality of sample preparation.

Loose packed columns experience variations in flow which cause variable analyte retention within the packed bed and can result in inconsistent recovery. Ultimately, this results in poor reproducibility, repeated runs, increased troubleshooting and higher costs.

The Microlute® CP range of polymeric SPE products overcomes these challenges through its innovative composite technology designed to improve the consistency and reliability of chromatographic analysis.

Providing a step change in performance, Microlute® CP combines chromatographically active resin with inert polyethylene, forming a single uniform porous frit.

Key features of our composite technology:

  • Rigid structure - robust, single piece design eliminates compression providing consistent flow rates and uniform sample processing.
  • Embedded Resin - evenly distributed resin immobilised throughout the frit structure eliminates variability and poor recovery caused by channelling and voiding.
  • Consistent Bed Weight - precision manufacturing controls active resin delivery, guaranteeing accurate and consistent bed weights across the whole plate.

These features create consistent liquid flow, ensuring reproducibility through uniform analyte, solvent and resin interactions. Directly translating into greater reproducibility and increased confidence in your results. Each well delivers the same performance, so you can trust your SPE results from the first sample to the last. Minimising the need for repeat runs, reducing wasted solvents and consumables and reducing troubleshooting time.

To find out more, visit us at analytica, Hall A1, Stand 415, or visit the website

For further details and pricing, contact our sales team

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