Missed our webinar? Watch the recording: Detecting unexpected nitrosamine contamination

Chromatography

Missed our webinar? Watch the recording: Detecting unexpected nitrosamine contamination

01 Mar, 2025

Nitrosamines remain a critical concern across multiple industries, from pharmaceuticals to cosmetics, due to their potential carcinogenic risks. Regulatory bodies such as the FDA and EMA have established stringent thresholds, compelling manufacturers to implement advanced monitoring and detection strategies to ensure compliance.

One of the greatest challenges in nitrosamine analysis is detecting a nitrosamine that was not anticipated in a sample. While targeted testing via GC or LC can identify known nitrosamines - provided reference standards are available - unexpected nitrosamine contamination may go undetected.

Ellutia’s recent webinar explored innovative analytical approaches that enable the identification of potential nitrosamine contaminants without requiring specific reference standards.

Key topics covered in the webinar include:

  • How a non-targeted screening approach to nitrosamine analysis can help flag potential contamination
  • The operation of the Automated Total Nitrosamine Analyser (ATNA) and its ability to rapidly perform Apparent Total Nitrosamine Content (ATNC) analysis down to low ppb levels
  • Strategies to avoid false positives during ATNC analysis caused by compounds such as nitrites
  • How GC-TEA can be used to further analyse potential unexpected nitrosamine contamination
  • Real-world case studies where this technology successfully identified unexpected nitrosamines

The webinar also featured a live Q&A session with Ellutia’s Senior Application Chemist, Mr Jonathan Angove, addressing audience questions in real time.

Watch the webinar recording now

If you missed the live session, you can watch the full recording here.

For further details about the ATNA and how it can enhance your nitrosamine analysis, visit Ellutia’s website.

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