Operator-free GMP-Compliant Cell Sorting System Introduced
Jun 25 2020 Read 258 Times
With its new MACS® GMP Tyto® Cartridge, Miltenyi Biotec opens new possibilities for fluorescence-based, GMP-compliant cell sorting. Specifically developed for the MACSQuant® Tyto® Cell Sorter, the launch of the cartridge makes Miltenyi Biotec the first company ever to offer GMP-compliant multiparametric, fluorescence-based cell sorting under safe and sterile conditions.
To help researchers meet the requirements of regulatory authorities for cell manufacturing protocols, every MACS® GMP Tyto® Cartridge comes with a batch-specific certificate of analysis (CoA), a TSE risk statement, and a product information file (PIF). PIFs, provided for all MACS® GMP Products, have proven very useful in the discussions with regulatory authorities, as they give detailed information on raw materials, QC release testing, sterility testing, biocompatibility, endotoxin levels, packaging, transport, and shelf life.
The MACSQuant® Tyto® Cell Sorter with its patented microchip-based technology allows for high-speed, multiparameter cell sorting in a fully closed system. Cells remain inside the closed cartridge at all times during the sorting process, and no sheath fluid is present in the system. Miltenyi Biotec’s range of MACS® GMP Fluorescent Antibodies and MACS® GMP Tyto® Running Buffer complement the system to make sure that cells only come in contact with GMP-compliant products.
Due to the closed design of the cartridge, cell sorting using the MACSQuant® Tyto® Cell Sorter provides full operator and sample safety. The easy ‘plug-and-play’ format of the instrument, combined with automated cartridge alignment and operator-free sorting, makes cell sorting accessible to any lab professional, without intensive training.
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