Micro Bioreactor with Active Cooling at BPI Conference

TAP Biosystems announced introduced a new active cooling system for its ambr micro bioreactor at this year’s BioProcess International (BPI) Conference in Long Beach, CA. TAP Biosystems new active cooling system uses circulated chilled fluid to rapidly adjust and maintain the cell culture temperature to between 20ºC and 40ºC. The wider temperature range makes it possible to predict cells’ performance in large-scale bioreactors and optimise conditions for both increased protein production and modulation of product quality in mammalian cultures. The lower temperatures also add the potential to support optimisation of cell growth and protein expression with insect cell lines such as SF9, SF21 and Hi5.

Dr Barney Zoro, ambr Product Manager at TAP Biosystems, commented: "Scientists increasingly want to operate protein production or clone selection experiments at temperatures significantly lower than 37ºC, because the resulting metabolic shift can extend culture duration and provide superior product quality.”