• DART®-MS Analysis of Low Solubility, High Molecular Weight Compounds
    BioChromato’s ionRocket DART-MS system in use.
  • DART®-MS spectrum of titranylphthalocyanineat at 500°C DART®-SVP pre-set temperature: 400°C, ionisation mode: DART® (+).
  • The ionRocket DART-MS system simplifies sample preparation.

Mass Spectrometry & Spectroscopy

DART®-MS Analysis of Low Solubility, High Molecular Weight Compounds

Jan 12 2022

A new application report describes how the ionRocket sample preparation device from BioChromato Inc, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART®-MS), enables routine analysis of low solubility, high molecular weight compounds.

Phthalocyanine based pigments are widely used for organic semiconductors and organic electroluminescence displays due to their clearness, high light stability, and durability. However, the chemical structure of Phthalocyanine based pigments are difficult to analyse due to their high molecular weight and low solubility. The application report provides data illustrating how DART®-MS with ionRocket sample introduction enabled structural information to be determined concisely and rapidly. The analysis was done under atmospheric conditions, and without pre-treatment.

The BioChromato ionRocket is a temperature-heating device for direct thermal desorption and pyrolysis of samples, prior to ionisation and analysis by mass spectrometry. Using ionRocket a temperature gradient from ambient up to 600ºC can be achieved in just a few minutes. This enables insoluble, high molecular weight materials to be pyrolysed and then introduced into the DART®-MS gas stream.

To read an application report describing this work in full please visit

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