Mass Spectrometry & Spectroscopy

  • Reinvigorate High-end Protein Research with Expanded Analysis Capabilities

Reinvigorate High-end Protein Research with Expanded Analysis Capabilities

Aug 02 2019 Read 869 Times

Scientists in academic, government and biopharmaceutical laboratories who are faced with increasingly complex research challenges now have access to a digitally advanced Thermo Scientific™ Orbitrap Tribrid mass spectrometry (MS) platform that includes a new high-performance MS with inherent flexibility and built-in intelligence to enable critical insights and breakthroughs.

The new Thermo Scientific™ Orbitrap Eclipse™ Tribrid™ mass spectrometer features important advancements that improve system sensitivity over previous generations and expand its ability to characterise and quantify complex biomolecules and biological systems. These enhancements are ideal not only for native omics and translational research, but also for the structural and biopharmaceutical analysis of intact proteins and their complexes.

The real-time capabilities of the Orbitra Eclipse Tribrid mass spectrometer uses the latest, built-in intelligence-driven data acquisition strategies to enhance experimental efficiency and ultimately accelerate tandem mass tagging (TMT) for multiplexed quantitative analysis of proteomes. Peptide spectra are searched in real-time against a study-specific database. Those that match then proceed for further analysis, significantly increasing the speed of analysis and accuracy of results. In addition, the new system extends structural analysis up to m/z 8,000, which enables the isolation and selective dissociation of protein complexes into their individual components, as well as revealing further insights about their exact structure.

The Orbitrap Eclipse Tribrid mass spectrometer can be integrated into a laboratory's routine workflows with the Thermo Scientific™ Almanac web-based application, which allows users to view instrument operation and data acquisition in real-time and receive notifications on the status of runs. Almanac offers scientists the ability to conveniently improve visibility to the utilisation of their laboratory systems any time and from any location.

More information online: https://ilmt.co/PL/OJkj

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