Microscopy & Microtechniques

  • Hyperspectral Imaging of Gold Nanoparticles in Live Blood Cells

Hyperspectral Imaging of Gold Nanoparticles in Live Blood Cells

Jun 14 2017 Read 886 Times

The circulatory system is a vehicle for delivery of functionalised nanoparticles to targeted cells and tissues. The CytoViva Enhanced Darkfield Hyperspectral Microscope from Schaefer Technologie GmbH is a highly effective tool for optically imaging and spectrally characterising nanoparticles while in the bloodstream or in other complex environments. No fluorescent labelling or other sample preparation of the nanoparticles or the biological matrix is required when using this technique.


The microscope creates high signal-to-noise optical and hyperspectral images, which enable fast and direct observation of unlabelled gold nanoparticles in live blood cells (see in the figure). The hyperspectral images contain one full spectrum of the reflected light in each pixel of the image. This makes it easy to identify the spectral response of the nanoparticles, confirming their presence, and the way they interact with individual cells of the blood sample. It can also provide keen insight regarding the chemical stability of nanoparticles and their drug load or other surface functionalisation. Therefore, the CytoViva technology can help you to understand the nanoparticle efficacy when used as drug delivery vectors.

Please contact Schaefer Technologie GmbH to learn more about this imaging technology or to arrange for test imaging of your samples.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

LabAsia Buyers Guide 2018

October 2018

In This Edition Articles - Choosing the Optimum Plasma Spectrochemistry Technique for Measuring Elemental Impurities in Pharmaceuticals - Blue Jacaranda Seed Oil Analysed Using Comprehensive...

View all digital editions

Events

Cleanzone

Oct 23 2018 Frankfurt am Main, Germany

Chem-Lab-Analyt

Oct 29 2018 Moscow, Russia

Lab Innovations 2018

Oct 31 2018 Birmingham, UK

analytica China

Oct 31 2018 Shanghai, China

Lab Expo Tunisia

Oct 31 2018 Tunis, Tunisia

View all events