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Beckman Coulter Genomics, Inc and Genpathway, Inc are offering whole-genome chromatin immunoprecipitation sequencing (ChIP-Seq) services supporting genome-wide studies of transcription factor binding, gene
transcription and epigenetic events.
ChIP-Seq combines chromatin immunoprecipitation with ultra high-throughput next generation DNA sequencing to enable the study of complex interactions between proteins and nucleic acids. Mapping protein-DNA complexes in vivo builds a picture of the intricate network of interactions that regulate genes and genetic pathways in a sample. Comparing ChIP-Seq results from different conditions – diseased versus normal cells, for example – can reveal distinguishing patterns of genetic regulation that may be biologically significant.
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