News & Views
Partnership to Advance Gene Therapy Pipeline
Aug 19 2019 Read 447 Times
Biochromatography development and manufacturing company BIA Separations is collaborating with AveXis, a Novartis company, to enhance the commercial purification process for its gene therapy pipeline. The initiative will begin with a focus on Zolgensma® (onasemnogene abeparvovec-xioi), the first U.S. Food and Drug Administration-approved gene therapy indicated for the treatment of pediatric patients with spinal muscular atrophy (SMA) who are less than two years of age.
Zolgensma is a one-time infusion that provides a functional copy of the human SMN gene to halt disease progression through sustained SMN protein expression. BIA was selected as a partner for its expertise in viral and DNA purification, particularly adeno-associated virus (AAV), and chromatographic technology for the purification and analysis of biomolecules.
Aleš Štrancar, CEO of BIA Separations commented: “We are proud to have been selected to support AveXis’ gene therapy pipeline. We look forward to seeing how Zolgensma helps the SMA community and the whole BIA team is honored to be a part of this important work.”
Andy Stober, Senior Vice President of Technical Operations for AveXis added: “We are especially grateful that BIA Separations shared, and operated, with the same sense of urgency we did to help bring gene therapy to the SMA community. BIA’s experience with AAV purification and its chromatographic technology were important contributions and we look forward to our continued work together.”
Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.
In This Edition Chromatography - The Purification of Crown Ether Samples by a Quaternary Solvent Flash Chromatography System - New Wettable Phase Thrives in Water - Reduced Surface Activity...
View all digital editions
Mar 01 2020 Chicago, IK, USA
Mar 04 2020 Beijing, China
Mar 05 2020 New Delhi, India
Mar 11 2020 Guangzhou, China
Mar 16 2020 Tokyo, Japan