PFAS analysis using EPA Method 1633

EPA Method 1633 provides a highly efficient and precise method for the determination and quantification of per- and polyfluoroalkyl substances (PFAS) in samples that contain complex matrices. This method is widely recognised for its ability to accurately detect PFAS compounds, which are often present in very low concentrations and are difficult to isolate due to the complexity of the sample matrices. The method is particularly important given the increasing concerns over the environmental and health impacts of PFAS, which are persistent and bio-accumulative.

The InertSep series from GL Sciences is a renowned line of solid-phase extraction (SPE) cartridges that stand out in the market for their exceptional purity, consistency, and overall quality. These attributes make InertSep cartridges a preferred choice among analysts seeking reliable and reproducible results. Within the InertSep product line, InertSep WAX FF and GCB Stacked SPE cartridges are specifically optimised for PFAS analyses, providing fast flow rates and efficient cleanup from various sample types such as aqueous solutions, soil, food, and other complex matrices. The high recoveries ensure that significant portions of the PFAS present in the samples are successfully extracted, while the cleanup efficiencies minimise the presence of interfering substances that could affect the accuracy of the analysis.

Graphite Carbon Black (GCB) is a material known for its superior ability to remove impurities thus providing a clean sample for subsequent analysis.  InertSep GCB is an excellent choice for liquid chromatography-mass spectrometry (LC/MS) analysis, where the efficiency of sample cleanup is critical in obtaining accurate and reliable results. The excellent cleanup efficiency of InertSep GCB ensures that the samples are free from contaminants that could interfere with the detection and quantification of PFAS, thereby enhancing the overall reliability and sensitivity of the analysis.

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