Mixer Mill provides Rapid and Efficient Cell Disruption

Retsch’s mixer mill MM 400 is a true multi-purpose mill in the lab: it is used for mixing and homogenising powders and suspensions within seconds and is also ideally suited for the disruption of biological cells as well as DNA/RNA and protein recovery.

A new adapter now allows for simultaneous cell disruption of up to 8 x 30 ml cell suspension in 50 ml Falcon tubes with glass beads. The oscillation frequency of the mill of up to 30 Hz and the process time can be individually adjusted according to application requirements.

Depending on the type of cell (yeast, bacteria, microalgae, filamentous fungi) this method is greatly superior to manual procedures as it allows to reproducibly disrupt up to 240 ml of cell suspension within 20 seconds to 7 minutes without noticeable temperature increase. This highly flexible mixer mill accepts a variety of grinding jars and adapters and is also used for the homogenisation of plants, soft cell tissue but also of harder sample materials.