New LCMS Q-TOF System Combines Greater Accuracy with Higher Sensitivity

The new LCMS-9030 from Shimadzu is a research grade mass spectrometer designed to deliver high-resolution, accurate mass detection with incredibly fast data acquisition rates, allowing scientists to identify and quantify more compounds with greater confidence. It utilises the same engineering DNA as Shimadzu’s proven, rugged, high-performance triple quadrupole (LC-MS/MS) platform and integrates this with powerful TOF architecture to transform high mass accuracy workflows by achieving high-sensitivity, high-speed and high-resolution detection.

The system provides effortless performance through less need for calibration and easy switching between ionisation units.  It has been unveiled at the 66th ASMS Conference on Mass Spectrometry and Allied Topics from June 3-7 in San Diego, USA.

Greater accuracy and higher sensitivity

Ultra-fast (UF) acquisition rates and core ion beam technologies developed for the triple quadrupole platform have created new possibilities in quantitative mass spectrometry by delivering exceptional sensitivity, specific quantitation and enhanced target compound verification. The new LCMS-9030 Q-TOF builds on this proven platform by rethinking time-of-flight detection.

In the LCMS-9030, core ion beam technologies transition towards a unique approach in ion gating using UFaccumulation™  to create a precise pulse of ions in the flight tube optimised for high sensitivity and high resolution using iRefTOF™  reflectron technology. The iRefTOF™ generates an ideal reflectron field, delivering the highest resolution for the flight path with highly stable mass accuracy.

New solution for analysing even the most complex samples

By bringing together UF technologies and innovative TOF thinking, the LCMS-9030 represents a step-change in Q-TOF performance and capability by unlocking a new solution for analysing even the most complex samples. It integrates the world’s fastest and most sensitive quadrupole technology with TOF architecture.

“Our Q-TOF technology on the LCMS-9030 will push the boundaries further for high mass accuracy and high mass resolution detection, and will make an impact across all applications, from small molecule quantitation to complex intact protein analysis. This technology highlights Shimadzu’s passion for making something new and innovative as well as our commitment to making analysis better and promoting better science,” said Shuzo Maruyama, General Manager, Analytical & Measuring Instruments Division, Shimadzu Corporation.

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