Liquid handling automation supports NGS workflows

SPT Labtech and EMBL GeneCore are collaborating to advance fully automated genomics workflows, combining liquid handling technology with streamlined library preparation to improve efficiency, reproducibility and scalability in next-generation sequencing applications.

As part of the collaboration, EMBL GeneCore, the genomics core facility of the European Molecular Biology Laboratory, has installed SPT Labtech’s firefly®+ all-in-one liquid handling platform. The system will support the development and optimisation of automated protocols for challenging applications, including low-input and metagenomic samples.

Designed to simplify complex genomics workflows, the firefly+ platform integrates pipetting, dispensing, incubation and shaking capabilities within a single compact system. By combining multiple preparation steps into one automated workflow, the platform enables researchers to reduce manual intervention while maintaining sample quality and consistency.

The system will be used alongside New England Biolabs® (NEB) NEBNext® library preparation kits to support the development of high-quality sequencing workflows across a wide range of sample inputs. The combination is intended to improve workflow efficiency while reducing variability and unnecessary plastic consumption associated with manual processing.

For genomics laboratories, automation of sample preparation remains a key challenge, particularly when working with limited or complex samples. Fully walkaway workflows can help address these bottlenecks by improving standardisation and enabling laboratories to increase throughput without compromising data quality.

Vladimir Benes, Head of Genomics Core Facility (GeneCore) at EMBL, said: “The installation of SPT Labtech’s firefly+ platform as part of our collaboration underscores our commitment to remain at the forefront of scientific innovation. Fully walkaway automation will address key bottlenecks in genomics workflows, helping us develop high-quality, scalable NGS protocols.”

Morten Frost, Chief Commercial Officer at SPT Labtech, added: “This collaboration marks an important step towards advancing fully walkaway automation, providing end-to-end genomics workflows for a wider range of applications, including environmental and rare species research.”

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