Consortium Demonstrates Real Time Measurement of Tablet Coating Thickness

TeraView, along with its partners Oystar Manesty, Liverpool University and Cambridge University have successfully demonstrated the ability to measure in-line the coating thickness distribution on a batch of tablets within a

production scale coating pan in real time. Knowing and managing thickness variability is a key quality attribute for products whose coating thickness is directly related to their performance (e.g. controlled release products). Accessing quality based on the average thickness alone can lead to tablets being out of specification or excessively coated. The TeraView system incorporating the company’s proprietary terahertz sensor technology is said to offer flexibility and speed that make it ideal for use in process development, scale up, technology transfers and manufacturing. “We are very excited about the team’s achievements” said Dr Don Arnone, TeraView’s Chief Executive Officer.

” It is well documented that not all tablets in a batch are of the same quality, and this now offers a quick and easy way of measuring and ultimately controlling this variability. It builds on the considerable body of work to date with our existing pharma customers and with the FDA”. The project has been supported by the UK Technology Strategy Board (TSB).