Direct translocation of proteins into living cells
Primary rat monocytes were loaded with NGF using BioPorter®. NGF (FITC) and Nuclei (DAPI). Image from Böttger et al (2010).

Reagents

Direct translocation of proteins into living cells

10 Oct, 2024

BioPORTER® protein delivery reagent from AMSBIO is proven to efficiently transport functionally active proteins directly into living cells eliminating the traditional DNA transfection, transcription, and protein translation process.

Employing a unique lipid-based protein delivery system, BioPORTER® makes studying protein functionality faster and easier than ever before. Comprising a proprietary cationic lipid mixture that interacts non-covalently with the protein, BioPORTER® creates a protective vehicle for immediate protein delivery directly into the cell cytoplasm.

BioPORTER® has been demonstrated to be highly effective in delivering a diverse array of proteins, peptides, and other macromolecules into the cytoplasm of many different cells, retaining the structure of the proteins whilst leaving the transduced cells unharmed. The BioPORTER® Reagent is especially useful when studying protein function in cells that are difficult to transfect using traditional DNA transfection reagents, such as human dendritic cells.

Available either as a bulk reagent or convenient single-use QuikEase™ vials, BioPORTER® is extremely easy to use. For maximum speed and convenience, AMSBIO offers the BioPORTER QuikEase™ Kit. Each QuikEase kit contains 96 single reaction size vials that are pre-coated with BioPORTER® reagent. You can either separate each vial for single use or use the entire pack for high-throughput experiments. The BioPORTER QuikEase kit saves hours of time by eliminating the need to coat the BioPORTER® Reagent onto individual vials.

Read AMSBIO’s blog post to learn more about how BioPORTER® has been used in immune cell driven drug delivery for treating neurodegenerative disorders.

More information online

ILM Guide 2026/27

Explore our Digital Edition

Discover the latest news and research

Digital edition

Explore Our Other Sites

Envirotech Online
EU ETS benchmark update puts industrial emissions data under sharper scrutiny
Explore more Arrow
Pollution Solutions Online
Next-generation reverse osmosis membranes for more efficient and cost-effective seawater desalination
Explore more Arrow
Petro Online
From specification to certification: Ensuring jet fuel conformity with reliable flash point testing
Explore more Arrow
Chromatography Today
Non-invasive flowmeters for real-time monitoring
Explore more Arrow