Cleaner signals for multi-colour flow cytometry

Laboratory products

Cleaner signals for multi-colour flow cytometry

26 Jan, 2026

Thermo Fisher Scientific’s Invitrogen™ UltraComp eBeads™ Spectral Unmixing Beads, designed to make spectral and conventional flow cytometry more precise and reliable. These next-generation beads mimic real cells, helping researchers separate overlapping fluorescent signals, reduce background noise, and confidently quantify complex or rare cell populations.

High-parameter flow cytometry provides a detailed view of cellular phenotypes, but traditional compensation solutions can introduce errors or false signals. UltraComp eBeads address these challenges by offering bright, consistent fluorochrome signals with minimal autofluorescence. They support antibodies from mouse, rat, hamster, rabbit, and recombinant human sources and are compatible with all major laser lines, including UV, violet, blue, green, yellow-green, red, and IR.

Each drop contains both positive and negative populations, producing clear, distinct peaks for quick and easy panel setup - even for high-parameter experiments. Researchers in immunology, immuno-oncology, and flow cytometry core facilities can now streamline workflows while maintaining clean, reproducible data.

“UltraComp eBeads deliver the accuracy and reliability researchers need to tackle complex cellular analyses,” said Trisha Dowling, VP/GM, Flow and Imaging Technologies. “They provide clearer signals, fewer errors, and confidence in every experiment.”

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