CT scanner advances large animal disease research

A new computed tomography (CT) scanner installed at the University of Edinburgh’s Roslin Institute will enable higher-resolution imaging of large animals, supporting research with potential applications in both veterinary and human medicine.

The Siemens Healthineers SOMATOM X.ceed system, based at the Large Animal Research and Imaging Facility (LARIF), is designed to provide detailed 3D imaging of tissues and organs at a level comparable to clinical human scanners. It is the first veterinary research CT system equipped with laser guidance to assist in directing procedures such as biopsies.

Researchers say the technology will improve the precision and speed of imaging and interventional studies in large animal models used to investigate diseases including cancer, neurological conditions and cardiovascular disorders.

The facility will also support research in gene editing and gene therapy being developed at the Roslin Institute, helping to improve understanding of how experimental treatments may translate to human disease.

Dr Mark Gray from the Royal (Dick) School of Veterinary Studies said the scanner significantly enhances imaging capability within the institution’s research environment.

“This next-generation CT scanner enables significant improvements in image resolution compared with our previous scanning capabilities,” he said. “It greatly enhances our ability to perform interventional procedures with increased precision and efficiency, similar to those conducted on human patients.”

The system is expected to strengthen the University of Edinburgh’s position as a major centre for veterinary and biomedical imaging in Europe, alongside existing capabilities in human medical imaging.

Funded through a £800,000 Medical Research Council equipment grant, with additional university capital investment, the scanner will support a range of interdisciplinary ‘One Health’ research projects that link animal and human health.

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