• Latest Technology for Cell-based Assays in a Microplate Reader
    Figure 1. Atmospheric Control Unit (ACU) for BMG Labtech’s CLARIOstar and Omega series.
  • Figure 2. Example of ischaemia/reperfusion conditions mimicked in the CLARIOstar with ACU.

Laboratory Products

Latest Technology for Cell-based Assays in a Microplate Reader

Apr 17 2018

Cell-based assays have become an important application in the life science sector, from basic to top-level research. They are widely used in biotech companies and academic research institutions to monitor cell health in real-time. As experiments with living cells require constant physiological conditions, a precise gas control is essential. BMG LABTECH’s Atmospheric Control Unit (ACU) with unique features is available for all of the company’s life science and assays development microplate readers.

Why is an integrated atmospheric control essential?

When performing cell-based assays on a microplate reader, specific atmospheric and temperature conditions are required to keep cell cultures in the optimal environment. Replicating conditions matching those found in nature is necessary to avoid stress responses thus ensuring robust and reliable results. BMG LABTECH’s Atmospheric Control Unit enables the independent control of both oxygen and carbon dioxide concentrations within the plate reader and replaces the need for transferring plates between the incubator and the microplate reader, saving time and labour. It is the ideal solution for a wide range of applications, including studies involving long-term cell proliferation, hypoxia and standard cell growth.

Gas control for all requirements and any budget

All of BMG LABTECH’s life science and assay development plate readers provide enhanced possibilities for cell-based assays. The Omega series including the multi-mode plate readers FLUOstar® Omega and POLARstar® Omega are perfect instruments for multiplex assays including simultaneous reads of fluorescence, absorbance and luminescence, ideal for following reporter gene expression whilst following cell growth and proliferation.

The Atmospheric Control Unit is also compatible with the single-mode Omega readers, LUMIstar®, SPECTROstar® and NEPHELOstar® meaning the gas control technology is available to all researchers for single-mode or multi-mode microplate readers.

Exclusive features with the CLARIOstar

The same precise Atmospheric Control Unit with additional features is available on the CLARIOstar®. Atmospheric control on the CLARIOstar includes the additional capability to run gas ramps for ischemic reperfusion type experiments and also benefits by tracking real-time gas values directly in the MARS data analysis software. These features are unique to the CLARIOstar with ACU and provide unrivalled control, measurement and reporting of live cell-based assays in a microplate reader.

A solution for any application

With the CLARIOstar and Omega series researchers now have a wide choice of BMG LABTECH microplate readers for their specific cell-based applications – there is an instrument for any purpose and any budget.


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