Novel Separations and Ionisation Technologies to High Resolution Mass Spectrometry on Show at ASMS 

Waters Corporation at the 63rd conference of the Society of Mass Spectrometry announced the introduction of new technologies and innovations for mass spectrometry, intended to give laboratories greater levels of detail for every analysis.

Combining the benefits of high-resolution tandem mass spectrometry and ion mobility separation in a bench top instrument, the Waters® Vion IMS QTof Mass Spectrometer brings clarity and confidence to routine analyses. Ion mobility removes spectral interferences and generates collision cross-section (CCS) values for every ion, giving scientists more information than they can get from traditional LC-MS experiments.

The UNIFI® Scientific Information System, Version 1.8, is a new release of the software with features intended to enhance laboratory productivity.  Today's announcement coincides with the introduction of the Vion™ IMS QTof Mass Spectrometer which is the first Waters mass spectrometer to be fully supported on UNIFI.

New features of this release of UNIFI software include: Support of  the Vion IMS QTof MS System;  native atmospheric pressure gas chromatography (APGC) control, time-of-flight (Tof) multiple reaction monitoring (MRM) support, support of collision cross section (CCS) data, and Tof quantitative and qualitative workflows providing a comprehensive, single software solution.

Combining direct-from-sample ionisation with high performance time-of-flight mass spectrometry and powerful, intuitive analytics, the Rapid Evaporative Ionisation Mass Spectrometry™ (REIMS™) Research System with iKnife™ Sampling System eliminates the need for sample preparation and chromatographic separation, providing food, microbiology and tissue researchers with near-instantaneous data acquisition.

Using Waters REIMS Research System with iKnife Sampling, researchers can quickly and easily differentiate samples from one another and confidently identify the differentiating features, allowing greater insight into the chemical and biological systems under investigation. In REIMS, direct, rapid heating of the samples leads to the formation of vapour that is rich in sample-specific chemical information. The vapour is taken directly into the mass spectrometer (Xevo® G2-XS QTof or SYNAPT® G2-Si HDMS) where the molecules are analysed by time-of-flight mass spectrometry.

The Oasis® PRiME HLB, a first-of-its-kind, next-generation solid phase extraction (SPE) product that provides cleaner samples in less time and with less effort for LC and LC-MS analyses. Oasis PRiME HLB cartridges and multiwell plates simplify and speed up extraction protocols to ensure consistent, reproducible LC and LC-MS results.