One sample, endless insights: Multiomics made simple

In drug discovery and disease research, precious samples are often irreplaceable. A single biopsy, rare cell population, or limited tissue specimen may hold answers critical to understanding disease mechanisms - but dividing it across multiple assays can dilute insight.

Thermo Fisher Scientific’s Sequential Protein/DNA/RNA Extraction Kit changes that. For the first time, researchers can extract protein, DNA, and RNA sequentially from the same sample, generating genomic, transcriptomic, and proteomic data without compromise. This enables direct, layer-to-layer comparison of molecular signals, helping scientists uncover connections that were previously difficult to see.

The kit’s magnetic bead workflow removes the need for centrifugation, streamlines processing, and can be automated - giving labs more throughput without extra complexity. Extracted DNA and RNA are ready for next-generation sequencing, while recovered proteins are compatible with mass spectrometry, supporting the critical workflows that drive drug discovery, biomarker identification, and translational research.

Dr Osamu Ohara of the Kazusa DNA Research Institute explained:

“This kit lets us recover DNA, RNA, and protein from the same sample in solution, ready for analysis immediately - saving both time and precious material.”

By making the most of every sample, the Sequential Protein/DNA/RNA Extraction Kit helps researchers connect molecular insights across biological layers, accelerate discoveries, and improve reproducibility - all from a single piece of material.    

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