News & Views

  • Mike Westby

Award to Boost Technology Targeting Antibacterial Resistance

Oct 14 2017 Comments 0

Up to £945,000 has been awarded to Centauri Therapeutics Ltd, a company focused on the treatment of infectious diseases and cancer, under Innovate UK’s Biomedical Catalyst (BMC) programme. The award, alongside backing from the Company’s investors, will co-fund research to generate a clinical candidate drug against Gram-negative bacteria- a major cause of mortality in hospital-acquired pneumonias - using the Company’s Alphamer™ technology. This drug mechanism utilises chemically synthesised molecules to redirect pre-existing antibodies to pathogens in a specific manner that elicits an immune response. This immune response will mediate destruction of the bacteria to clear the infection, while working in conjunction with existing antibiotics to reduce the dose and duration of therapy. Unlike traditional vaccines, this approach aims to treat infected patients and has the potential to elicit a broader immune response than monoclonal antibodies alone.

Dr Mike Westby, Director and CEO of Centauri Therapeutics said: “The lack of new antibiotics combined with increasing incidence of bacterial resistance in the clinic has been termed ‘the perfect storm’ and there is an urgent need for innovative methods and efficacious therapies. The BMC Award is a significant recognition of Centauri’s scientific expertise and demonstrates the UK government’s confidence in our team’s ability to combat antibacterial resistance and deliver novel treatments for patients.”

Total costs for the project titled ‘Optimisation of antibody recruiting molecules as immunotherapeutics’ are estimated at £1.35M. The co-funding from Innovate UK will cover up to 70% of this, with Centauri’s investors supporting the remaining 30% of the project costs over a two-year period.

Read comments0

Do you like or dislike what you have read? Why not post a comment to tell others / the manufacturer and our Editor what you think. To leave comments please complete the form below. Providing the content is approved, your comment will be on screen in less than 24 hours. Leaving comments on product information and articles can assist with future editorial and article content. Post questions, thoughts or simply whether you like the content.


Digital Edition

Labmate UK & Ireland October / November 2017

November 2017

In this Issue Articles - How to Achieve Ultimate PCR Optimisation Spotlight Features - Incubators, Freezers & Cooling Equipment - Balances & Strain Gauges - Proteomics, Genomics & Mic...

View all digital editions

Events

MSACL 2018 US

Jan 21 2018 Palm Springs, CA, USA

HTC-15

Jan 24 2018 Cardiff, UK

Arab Health

Jan 29 2018 Dubai International Convention & Exhibition Centre

SLAS 2018

Feb 03 2018 San Diego, CA USA

MEDLAB MIDDLE EAST

Feb 05 2018 Dubai, UAE

View all events